Scientist
Apply Job ID 38930 Date posted 04/28/2026Job Family:
Scientist
Travel Required:
Clearance Required:
What You Will Do:
We are currently searching for a Scientist. The individual will independently provide support services to satisfy the overall operational objectives of the National Institute on Aging (NIA). The primary objective is to provide services and deliverables through performance of support services. This is a full-time, on-site opportunity in Baltimore, MD.
Select, devise, plan, and execute experiments in the context of the laboratory’s overall research program.
Perform a variety of experimental procedures including isolation and analysis of DNA, RNA, and protein by routine molecular biology methods, such as in situ hybridization, RNA Scope, immunohistochemical staining, automated DNA sequencing, cell culture, Southern, Northern and Western blot analysis, real-time Reverse Transcription-Polymerase Chain Reaction (RT-PCR), and protein extraction.
Complete a variety of experimental procedures on the expression of insulin isoforms and genetics of insulin signaling in the brain Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI).
Function as primary investigator in animal research studies and develop animal model systems, as related to neuroscience and optogenetics; submit and gain approval of laboratory animal study protocols.
Determine experimental approaches to be applied to evaluate the hypotheses under investigation and for planning and carrying out those experiments
Evaluate new types of experimental approaches and recommend changes to Standard Operating Procedures (SOPs) based on knowledge of scientific literature, available facilities, and research needs.
Perform analysis and interpretation of the data for developing strategies for pursuing significant observation and for ensuring accuracy and reproducibility of results.
Evaluate new types of experimental approaches and recommend changes to SOPs based on knowledge of scientific literature, available facilities, and research needs.
Communicate results and methods in reports, presentations, and manuscripts for peer-reviewed publications and at local, national, and international meetings.
Coordinate the training of laboratory personnel, research associates, post-doctoral fellows, visiting scientists, students, and others in specialized technologies.
Independently direct and conduct special research projects that have a high priority for the laboratory with special emphasis on the development of novel research treatments.
Manage scientific equipment and resources (e.g., reagents, stocks of frozen cells, animal samples) including acquisition, documentation, and storage.
Oversee data management for all processed compounds.
Collaborate with staff to confirm assay results.
Evaluate new techniques, instruments, and search literature to propose, design, and test alternative assays for difficult screening targets; confirm assay results; develop secondary assays.
Coordinate projects being developed in the laboratory, propose Stop and Reverse (SAR) strategies and monitor their progress.
Author papers and abstracts detailing research efforts and results for publication in peer-reviewed journals.
Produce research reports and regularly communicate results to staff and collaborators.
Manage a portfolio of research grants in the assigned area.
What You Will Need:
Master’s degree in biochemical sciences, neuroscience, physiology, cognitive science, and biopsychology or related field.
At least SIX (6) years of biomedical research experience.
Proven ability in managing and coordinating interdisciplinary research projects.
Experience in multiple aspects of manuscript development activities.
Author/ co-author on peer reviewed journals.
Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred
What Would Be Nice To Have:
Ph.D. in chemistry, biochemistry, biology, genetics, neuroscience, or related field, preferred.
Knowledge of bioinformatics, and application to large proteomics and gene data sets, and their interpretation.
Proficient with MS Office Suite.
Excellent analytical, organizational and time management skills.
Strong communication skills, written and oral.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
Position may be eligible for a discretionary variable incentive bonus
About Guidehouse
Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
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