Platform Infrastructure Engineer
Apply Job ID 34370 Date posted 12/08/2025Job Family:
Database Administration (Digital)
Travel Required:
Clearance Required:
What You Will Do:
We are searching fora Platform Infrastructure Engineertosupport future opportunities. The person in this role will install, configure, optimize, and validate scientific platforms and underlyingon-premises and cloud-basedinfrastructureto ensure high availability, security, and performance for biomedical research and laboratory automation.Thisposition will be basedinBethesda,MD.
Design, implement, and optimize platform infrastructure, including migrating from legacy on-premise solutions to cloud environments (AWS, Azure, GCP) with high reliability and scalability.
Install and configure high-throughput screening (HTS) platforms, Automated Compound Management Systems, and platform components.
Set up and maintain networking equipment, cloud platform resources, and high-performance computing (HPC) clusters supporting scientific platforms.
Perform platform validation, integration testing, and maintain audit-ready documentation, including support for Authority to Operate (ATO) processes.
Implement and maintain monitoring, backup/restore, and change control processes using tools such as Nagios, Ganglia, XDMoD, and SIEMs.
Apply industry-standard and NIH-mandated security measures, conduct vulnerability assessments, and ensure compliance with NIST, CIS, and other frameworks.
Automate deployment workflows using tools like Ansible, Terraform, and Packer.
Collaborate with vendors, researchers, and internal teams for upgrades, lifecycle management, and solution transitions.
Lead quarterly patch cycles and coordinate with external stakeholders.
Support troubleshooting, diagnostics, and technical support for scientific platforms.
What You Will Need:
Bachelor degree in Engineering, Information Technology, Computer Science, or related field.
A minimum of TWO (2) years of platform engineering or systems integration experience; experience with cloud services and HPC environments preferred.
Experience with laboratory automation and regulated change/configuration management.
Familiarity with scripting (PowerShell, Python, Bash, Ruby) and containerization (Docker, Kubernetes).
Knowledge of cybersecurity best practices, zero trust architecture, and compliance frameworks (NIST, CIS, ISO 2700 Series).
Experience with monitoring, ITSM tools (ServiceNow, Remedy), and infrastructure as code.
What Would Be Nice To Have:
Experience supporting cloud services (AWS EC2, EKS, IAM, S3, RDS, etc.).
Knowledge of HPC architecture, performance optimization, and scientific workflow support.
Strong communication, documentation, and multitasking skills.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
Position may be eligible for a discretionary variable incentive bonus
About Guidehouse
Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
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