Bioinformatics Scientist
Apply Job ID 40651 Date posted 06/18/2026Job Family:
Scientific Research & Analysis
Travel Required:
Clearance Required:
What You Will Do:
We are currently searching forBioinformatics Scientisttoprovidebioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis. This is a full-time, on-site opportunity inDurham, NC.
Collaborate with scientists to design, analyze,manageand interpret all types of data.
Conduct analyses on NextGen sequencing data including data derived inChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models.
Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries.
Conduct analysis and interpretationondata from genomic platforms including expression, exon, tiling,promoterandothersarray types.
Work independently with research groups to develop, implement, and refine analyticalpipelinefor single cell data analysis.
Develop,optimize, andmaintainbioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS,scRNA-seq, multi-omics).
Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights.
Collaborate with scientists and researchers to design experiments, selectappropriate analyticalapproaches, and troubleshoot methodologies.
Integrate and analyze diverse genomic and multi-omicdatasets, including sequencing and public data sources.
Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation.
Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences.
Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs.
Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques.
Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications.
Support interdisciplinary collaborations and contribute to advancing researchobjectivesaligned with organizationalmission.
Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.
What You Will Need:
Master’s degree in bioinformatics,biostatistics,computationalbiologyor biological/life science.
At leastTWO (2)years ofdata analysisexperience.
Advancedproficiencyindisciplinessuch asstatistical modeling, machine learning, and integrative analysis to extract biologically meaningfulinsights from complex cellular systems.
Knowledgeable with avariety of next gen sequencing techniques.
Experience working withanalyticaltools,softwareand platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat /Scanpy,Linux,Unix,Bioconductor,Cloud computing,High-PerformanceComputing (HPC).
Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred
What Would Be Nice To Have:
PhD preferred
Strong verbal and writtencommunication skills
Familiar with multiplenext gen sequencingtechniques
Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
Position may be eligible for a discretionary variable incentive bonus
About Guidehouse
Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
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